Interactome CM2D3

Interactome CM2D3

Furnishing the human interactome with structural models of protein complexes

New Database with structural models of protein complexes derived by comparative modeling and data driven docking.

Search your interactions

Enter a list of interactions. Every interaction in a separate line, as a pair of space-separated Uniprot Entries or Uniprot Accessions IDs

Example Uniprot Entry
ARHGB_HUMAN RHOA_HUMAN
NXT2_HUMAN UBP54_HUMAN

Example Uniprot Accession
Q9H8T0 Q96ED9
O15273 P46108

Search for interactions with other proteins

Enter a list of Uniprot Entries or Uniprot Accessions.


Example Uniprot Entry
NXT2_HUMAN
AKTIP_HUMAN

Example Uniprot Accession
Q9H8T0
Q96ED9

How to search the DATABASE

Users can retrieve the information of protein complexe querying by a particular pairs of proteins using the Uniprot entry gene ID space separated:

ARHGB_HUMAN RHOA_HUMAN
NXT2_HUMAN UBP54_HUMAN


Besides using a given pair(s), users can retrieve all the interactions for a given protein providing also the Uniprot entry gene ID:

NXT2_HUMAN
AKTIP_HUMAN


The server returns a list of structural models that users can browse including the visualization of the structure of the complex on a Mol* applet.


About InteractomeCM2D3

Interactome CM2D3 (Comparative Modeling and Data-Driven Docking) database.
This resource compiles structural models of protein complexes derived both by comparative modeling and docking using our original methods MODPIN and VD2OCK.

Comparative Modeling

Homology modeling with MODPIN, a set of python script to model and analyze protein-protein interactions.

Data Driven Docking

Protein docking with VD2OCK, a guided protein-docking algorithm to model quaternary structure of binary complexes.